I did some brief searching on the forums for some information about this but was unable to find anything. Is it safe to run fuel injector cleaner/BG 44k in the gas of an rx8? I just want to make sure that it wont have any negative effect on the car.

 

Yes, it's perfectly safe following the instructions.
Many vendors on here sell it as do some Mazda dealerships as well.

See this thread as just one example of what can be found using the search function.
https://www.rx8club.com/showthread.p...ghlight=BG+44k