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A person with HHT has a tendency to form blood vessels that lack the capillaries between an artery and vein. This means that arterial blood under high pressure flows directly into a vein without first having to squeeze through the very small capillaries. This place where an artery is connected directly to a vein, tends to be a fragile site that can rupture and result in bleeding. We usually call a blood vessel that is abnormal in this way a telangiectasis (tel-AN-jee-eck-TAZE-ee-ya), if it involves small blood vessels. We tend to call it an arterioveneous malformation (AVM) if involves larger blood vessels. So, an AVM might be thought of as a big telangiectasis. The basic abnormality in the blood vessel is the same.
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thats part of it...
But it will affect people differently..not every has the problem in the same area. The person who i know who has it had a stroke becuase of it and also has heart/liver/GI problems and bleeding. There is a lot more info on the site too.
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